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ra0001p151 | (1) | WCRB2014

Detection of ZP-autoantibody in the sera from infertile women using a human multiepitope peptide as antigen

Xu Wan Xiang , Wang Jian , Zhu Weijie , Chang Xiaoxue , Sun Xiaoxi , Gupta Satish K , He Yaping , Tang Haiping , Shi Huijuan , Gu Shaohua , Ji Chaoneng , Xie Yi

Background: The role of autoantibodies against zona pellucida (ZP) in infertility and success of IVF is debatable. In the present study, a novel recombinant human zona protein is used to address this issue.Materials and methods: Fourteen serum samples positive for porcine ZP, six from infertile patients, and 20 from healthy women were analysed. Sera were tested for their reactivity against a recombinant multi-epitope peptide (named ZPCP7) composed of ten...

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Detection of ZP-autoantibody in the sera from infertile women using a human multiepitope peptide as antigen

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